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CD112 (DMC224) IgG1 Chimeric mAb

Anti-CD112 (DMC224) IgG1 Chimeric Monoclonal Antibody
5/5

¥3,900.00

Cat.#:  28173

   Size:   100 μg

In Stock

          Product Description          
目录:   28173
产品名称:   CD112(DMC224) IgG1 Chimeric Monoclonal Antibody
基因符号:   NECTIN2; HVEB; PRR2; PVRL2; PVRR2
描述:    CD112 antibody(DMC224) IgG1 Chimeric Monoclonal Antibody
背景:    This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus; and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants; encoding different isoforms; have been characterized.
经过测试的应用:    ELISA; Flow Cyt
推荐稀释度:    ELISA 1:5000-10000; Flow Cyt 1:100
种属反应性:    Rabbit
亚型:    Rabbit:Human Fc chimeric IgG1
纯化:    Purified from cell culture supernatant by affinity chromatography
种属反应性:    Human CD112
成分:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
储存和运输:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. CD112 protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis with CD112 (DMC224) on Expi293 cells transfected with human CD112 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram), and  Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram).
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