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ERBB2(D769H)

Anti-ERBB2(D769H) Mouse Monoclonal Antibody
5/5

¥4,800.00

Cat.#:  26381

   Size:   100 μl

In Stock

          Product Description          
ERBB2(D769H)
货号:  26381
基因符号:  ERBB2/HER2/Neu/c-Neu
描述:   ERBB2(D769H) 小鼠单克隆抗体
背景:   The HER-2/neu oncogene, a member of the epidermal growth factor receptor or erb-B gene-like family, encodes a transmembrane tyrosine kinase receptor that mediates extracellular signals activated by epidermal growth factors. Her2 abnormal has been strongly associated with many malignant tumors, especially with breast cancers. The expression level of Her2 is an important criteria in clinic evaluating of the progression of breast cancer.
免疫原:   A synthetic peptide from the internal region of ERBB2 which includes the mutation of D769H, human origin.
经过测试的应用:   ELISA, WB, IHC
推荐稀释度:    ELISA: 1:1000-1:2000 WB: 1:500-1:1000 IF: 1:25-1:50
浓度:   1 mg/ml
种属反应性:   Mouse
形式:   Liquid
克隆性:   Monoclonal
亚型:   IgG
纯化::   Purified from ascites
Preservative: No
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
种属反应性:  Recognizes D769H mutant, but not wild type ERBB2 of vertebrates.
储存条件::   Store at -20°C. Avoid repeated freezing and thawing
Western blot:   Western blot analysis of recombinant ERBB2(D769H) and wild type proteins. Purified His-tagged ERBB2(D769H) protein (lane 1) and corresponding wild type protein (lane 2) were blotted with ERBB2(D769H) monoclonal antibody (货号26381). Immunofluorescence:   Immunofluorescence of cells expressing ERBB2 proteins with ERBB2(D769H) antibody. HEK293T cells were transfected with pCDNA3-GFP-ERBB2 (WT) plasmid (left column) or pCDNA3-GFP-ERBB2(D769H) plasmid (right column), then fixed and stained with ERBB2(D769H) monoclonal antibody (货号26381).
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