武汉费斯德生物科技有限公司， NewEast Biosciences 中国办事处 

邮箱: 2716620741@qq.com

咨询: 027 – 63497286 

英文
英文

Product Categories

Download Files

DataSheet

MSDS

ATM(F858L)

Anti-ATM(F858L) Mouse Monoclonal Antibody
5/5

¥4,800.00

Cat.#:  26141

   Size:   100 μl

In Stock

          Product Description          

ATM(F858L)

货号:  26141
基因符号:  ATM
描述:   ATM(F858L) 小鼠单克隆抗体
背景:   Ataxia telangiectasia mutated (ATM) is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks. It phosphorylates several key proteins that initiate activation of the DNA damage checkpoint, leading to cell cycle arrest, DNA repair or apoptosis. Activity of ATM protein is under tight control, and mutation of ATM can cause disease such as Ataxia telangiectasia (AT) and cancers.
免疫原:    A synthetic peptide from the internal region of ATM which includes the mutation of F858L, human origin.
经过测试的应用:   ELISA, WB, IHC
推荐稀释度：   
ELISA: 1:1000-1:5000
WB: 1:100-1:1000
IHC: 1:50-1:100
浓度:   1 mg/ml
种属反应性:   Mouse
形式:   Liquid
克隆性：   Monoclonal
亚型:   IgG
纯化::   Purified from ascites
Preservative: No
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
种属反应性:  Recognizes ATM(F858L), but not wild type ATM protein from vertebrates.
储存条件::   Store at -20°C. Avoid repeated freezing and thawing
Western blot:  

Western blot analysis of recombinant ATM(F858L) and wild type proteins. Purified His-tagged ATM(F858L) protein (amino acids 2400-3056, lane 2) and corresponding wild type protein (lane 1) were blotted with ATM(F858L) mouse monoclonal antibody (货号26141).

Immunofluorescence:  

Immunofluorescence of cells expressing ATM(F858L) protein with ATM(F858L) antibody. HEK293T cells were transfected with pCDNA3-GFP-ATM (WT) plasmid (left column) or pCDNA3-GFP-ATM(F858L) plasmid (right column), then fixed and stained with ATM(F858L) monoclonal antibody (货号26141).

          Related Products          

Related products

          Publications          
Circulating Tumor Cell Separator
(CTC Separation by Filtration)
Antibody Internalization Labeling Kit
Name Brand Lab Supplies
Biosimilar Reference Antibodies
Synthetic Nanodisc
No Acetylation cAMP/cGMP EIA Kits
按字母选择
Main Menu

产品分类

应用领域

相关信息

联系我们

Copyright © 2010-2024
NewEast Biosciences | All rights reserved

GTPase & Oncogene | cGMP & cAMP | Nanobody | Bioactive Transmembrane Proteins | Circulating Tumor Cells | Lipoproteins