关于 NewEast Biosciences
武汉费斯德生物科技有限公司是美国NewEast Biosciences在中国的办事处。NewEast Biosciences 在十二年前率先研发俩种独特的抗体。这俩种抗体仅仅识别活性的GTP酶或者突变的Oncogene。 GTP酶涉及(1)响应细胞表面受体激活的信号转导,包括跨膜受体,例如介导味觉、嗅觉和视觉的那些,(2)核糖体的蛋白质生物合成,(3)调节细胞分化、增殖、分裂和运动,(4)蛋白质通过膜的易位,(5)细胞内囊泡的运输,以及囊泡介导的分泌和摄取,通过GTP酶控制囊泡外壳组装。Oncogene侧是诱发癌症的基因。
我公司将向你提供以下的独一无二的三种抗体或者试剂盒: (1) 仅识别 GTP酶的活性构型的产品, 它可以让你能够量化GTP酶在细胞中的活性和分布。(2) 识别突变 Oncogene蛋白, 但不认识相应野生型的抗体。 (3) 对 cAMP 和 cGMP 具有超亲和力(无需乙酰化)ELISA检测试剂盒。这些产品被将近一千篇同行评议的文章所引用。
¥3,900.00
目录: 28535 |
产品名称: ADAM9(DM192) Rabbit Monoclonal Antibody |
基因符号: CORD9; MCMP; MDC9; Mltng |
描述: ADAM9 antibody(DM192) Rabbit Monoclonal Antibody |
背景: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins; and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions; including fertilization; muscle development; and neurogenesis. The protein encoded by this gene interacts with SH3 domain-containing proteins; binds mitotic arrest deficient 2 beta protein; and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. Several alternatively spliced transcript variants have been identified for this gene. |
经过测试的应用: ELISA; Flow Cyt |
推荐稀释度: ELISA 1:5000-10000; Flow Cyt 1:100 |
种属反应性: Rabbit |
亚型: Rabbit IgG |
纯化: Purified from cell culture supernatant by affinity chromatography |
种属反应性: Human ADAM9 |
成分: Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization. |
储存和运输: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). |
![]() Figure 1. ADAM9 protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis with ADAM9 (DM192) on Expi293 cells transfected with human ADAM9 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram), and Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram). |