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Bioactive Multipass Transmembrane Proteins

Membrane proteins (MPs) are the gatekeepers of cells and play an important role in a variety of cellular functions such as material transport, signal transduction, and cell-to-cell recognition (Figure 1). Abnormal functions of MPs often lead to the occurrence of diseases. Therefore, MPs account for more than 60% of all the current FDA-approved drug targets and 90% of the antibody drug targets.

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