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KIT(V560DEL)

Anti-KIT(V560DEL) Mouse Monoclonal Antibody
5/5

¥4,800.00

Cat.#:  26289

   Size:   100 μl

In Stock

          Product Description          
KIT(V560DEL)
货号:  26289
基因符号:  C-Kit; CD117; KIT; PBT; SCFR
描述:   KIT(V560DEL) 小鼠单克隆抗体
背景:   Tyrosine-protein kinase Kit, also known as proto-oncogene c-Kit or CD117 or Mast/stem cell growth factor receptor (SCFR), is a receptor tyrosine kinase protein that in humans is encoded by the KIT gene. Activating mutations in this gene are associated with gastrointestinal stromal tumors, testicular seminoma, mast cell disease, melanoma, acute myeloid leukemia, while inactivating mutations are associated with the genetic defect piebaldism.
免疫原:   A synthetic peptide from the internal region of KIT which includes the deletion of V560, human origin.
经过测试的应用:   ELISA, WB, IHC
推荐稀释度:    ELISA: 1:1000-1:5000 WB: 1:500-1:1000 IHC: 1:50-1:100
浓度:   1 mg/ml
种属反应性:   Mouse
形式:   Liquid
克隆性:   Monoclonal
亚型:   IgG
纯化::   Purified from ascites
Preservative: No
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
种属反应性:  Recognizes V560DEL mutant, but not wild type KIT of vertebrates.
储存条件::   Store at -20°C. Avoid repeated freezing and thawing
Western blot:   image.png Western blot analysis of recombinant KIT(V560DEL) and wild type proteins.Purified His-tagged KIT(V560DEL) protein (lane 1) and corresponding wild type protein (lane 2) were blotted with KIT(V560DEL) monoclonal antibody (货号 26289). Immunofluorescence:   image.png Immunofluorescence of cells expressing KIT proteins with KIT(V560DEL) antibody. HEK293T cells were transfected with pCDNA3-GFP-KIT (WT) plasmid (left column) or pCDNA3-GFP-KIT(V560DEL) plasmid (right column), then fixed and stained with KIT(V560DEL) monoclonal antibody (货号26289).
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