PTEN (R130G) 货号:  26312 基因符号: PTEN, 10q23del, BZS, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1, MMAC1, PTEN1, TEP1 描述: PTEN (R130G) Mouse Monoclonal Antibody 背景: Phosphatase and tensin homolog (PTEN) was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency.I t is one of the most commonly lost tumor suppressors in human cancer. During tumor development, mutations and deletions of PTEN occur that inactivate its enzymatic activity leading to increased cell proliferation and reduced cell death. Frequent genetic inactivation of PTEN occurs in glioblastoma, endometrial cancer,and prostate cancer; and reduced expression is found in many other tumor types such as lung and breast cancer. 免疫原: A synthetic peptide from the internal region of PTEN which includes the mutation of R130G, human origin. Tested applications: ELISA, WB Recommended dilutions: ELISA:  1:1000-1:5000 WB:     1:500-1:1000 浓度: 1 mg/ml 种属反应性: Mouse 克隆性： Monoclonal 纯化:: Purified from ascites 形式: Liquid Storage buffer:  Preservative: no 成分: PBS (without Mg2+ and Ca2+),pH 7.4, 150 mM NaCl, 50% glycerol 种属反应性: Recognizes R130G mutant,but not wild type PTEN from vertebrates. 储存条件:: Store at -20°C. Avoid Western blot: Western blot analysis of recombinant PTEN R130G) and wild type proteins. Purified His-tagged FGFR1 (R130G) protein (lane 2) and corresponding wild type protein (lane 1) were blotted with PTEN (R130G) monoclonal antibody (货号26312).