| 目录: 12219 |
| 产品名称: Mouse ROR2 Protein |
| 规格: 10 µg, 50 µg and 100 µg |
| 基因符号: Ntrkr2 |
| Target: ROR2 |
| UNIPROT ID: Q9Z138 |
| 描述: Recombinant mouse ROR2 protein with C-terminal 6xHis tag |
| 背景: Enables Wnt-protein binding activity; frizzled binding activity; and mitogen-activated protein kinase kinase kinase binding activity. Involved in positive regulation of canonical Wnt signaling pathway and positive regulation of transcription, DNA-templated. Acts upstream of or within several processes, including cartilage condensation; cell surface receptor signaling pathway; and embryonic morphogenesis. Predicted to be located in several cellular components, including dendrite; microtubule; and neuronal cell body. Predicted to be part of receptor complex. Predicted to be integral component of plasma membrane. Is expressed in several structures, including alimentary system; embryo mesenchyme; genitourinary system; neural ectoderm; and sensory organ. Used to study autosomal recessive Robinow syndrome. Human ortholog(s) of this gene implicated in autosomal recessive Robinow syndrome; brachydactyly type B1; and cleft palate. Orthologous to human ROR2 (receptor tyrosine kinase like orphan receptor 2). [provided by Alliance of Genome Resources, Apr 2022] |
| Species/Host: HEK293 |
| Molecular Weight: The protein has a predicted molecular mass of 42.0 kDa after removal of the signal peptide. The apparent molecular mass of mROR2-His is approximately 35-55 kDa due to glycosylation. |
| Molecular Characterization: Mouse ROR2(Glu34-Gly403) 6×His tag |
| 纯化:: The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
| 储存和运输: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Figure 1. Mouse ROR2 Protein, His Tag on SDS-PAGE under reducing condition. |
