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JAK2(R683S)

Anti-JAK2(R683S) Mouse Monoclonal Antibody
5/5

¥4,800.00

Cat.#:  26315

   Size:   100 μl

In Stock

          Product Description          
JAK2(R683S) Monoclonal Antibody
货号:  26315
规格:  100 µL
基因符号:  JAK2, JTK10, THCYT3
描述:   JAK2(R683S) 小鼠单克隆抗体
背景:   JAK2 is a non-receptor tyrosine kinase. It is a number of the Janus kinase family and has been implicated in ssignaling by members of the type II cytokine receptor family, the GM-CSF receptor family, the gp130 receptor family, and the single chain receptors. JAK2 orthologs have been identified in all mammals for which complete genome genome data are available. Mutations of JAK2 have been implicated in polycythemia vera, essential thrombocythemia, and myelofibrosis as well as other myeloproliferative disorders.
免疫原:   A synthetic peptide from the internal region of JAK2 which includes the mutation of R683S, human origin.
经过测试的应用:   ELISA, WB, IHC
推荐稀释度:    ELISA: 1:1000-1:2000 WB: 1:500-1:1000 IHC: 1:50-1:100
浓度:   0.5 mg/ml
种属反应性:   Mouse
形式:   Liquid
克隆性:   Monoclonal
亚型:   IgG
纯化::   Purified from ascites
Preservative: No
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
种属反应性:  Recognizes R683S mutant, but not wild type JAK2 of vertebrates.
储存条件::   Store at -20°C. Avoid repeated freezing and thawing
Western blot:   Western blot analysis of recombinant JAK2(R683S) and wild type proteins. Purified His-tagged JAK2(R683S) protein (lane2) and corresponding wild type protein (lane1) were blotted with JAK2(R683S) monoclonal antibody (货号26314).
Immunofluorescence:   Immunofluorescence of cells expressing JAK2 proteins with JAK2(R683S) antibody. HEK293T cells were transfected with pCDNA3-GFP-JAK2(R683S) plasmid,pCDNA3-GFP-JAK2 (WT) plasmid, pCDNA3-GFP-JAK2 (R683T) plasmid or pCDNA3-GFP-JAK2 (R683G) plasmid, then fixed and stained with JAK2(R683S) monoclonal antibody (货号26314).
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