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CD45 (DM193) Rabbit mAb

Anti-CD45 (DM193) Rabbit Monoclonal Antibody
5/5

¥3,900.00

Cat.#:  28536

   Size:   100 μg

In Stock

          Product Description          
目录:   28536
产品名称:   CD45(DM193) Rabbit Monoclonal Antibody
基因符号:   B220; CD45; CD45R; GP180; L-CA; LCA; LY5; T200
描述:    CD45 antibody(DM193) Rabbit Monoclonal Antibody
背景:    The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth; differentiation; mitosis; and oncogenic transformation. This PTP contains an extracellular domain; a single transmembrane segment and two tandem intracytoplasmic catalytic domains; and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes; or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases; and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene; which encode distinct isoforms; have been reported.
经过测试的应用:    ELISA; Flow Cyt
推荐稀释度:    ELISA 1:5000-10000; Flow Cyt 1:100
种属反应性:    Rabbit
亚型:    Rabbit IgG
纯化:    Purified from cell culture supernatant by affinity chromatography
种属反应性:    Human CD45
成分:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
储存和运输:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with CD45 (DM193) on Expi293 cells transfected with human CD45 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
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