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CD160 (DMC270) IgG1 Chimeric mAb

Anti-CD160 (DMC270) IgG1 Chimeric Monoclonal Antibody
5/5

¥3,900.00

Cat.#:  28178

   Size:   100 μg

In Stock

          Product Description          
目录:   28178
产品名称:   CD160(DMC270) IgG1 Chimeric Monoclonal Antibody
基因符号:   BY55; NK1; NK28
描述:    CD160 antibody(DMC270) IgG1 Chimeric Monoclonal Antibody
背景:    CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich; glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells; spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16 cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab CD8brightCD95 CD56 CD28-CD27-cells. In tissues; CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules.
经过测试的应用:    Flow Cyt
推荐稀释度:    Flow Cyt 1:100
种属反应性:    Rabbit
亚型:    Rabbit:Human Fc chimeric IgG1
纯化:    Purified from cell culture supernatant by affinity chromatography
种属反应性:    Human CD160
成分:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
储存和运输:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with CD160 (DMC270) on Expi293 cells transfected with human CD160 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
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