关于 NewEast Biosciences
武汉费斯德生物科技有限公司是美国NewEast Biosciences在中国的办事处。NewEast Biosciences 在十二年前率先研发俩种独特的抗体。这俩种抗体仅仅识别活性的GTP酶或者突变的Oncogene。 GTP酶涉及(1)响应细胞表面受体激活的信号转导,包括跨膜受体,例如介导味觉、嗅觉和视觉的那些,(2)核糖体的蛋白质生物合成,(3)调节细胞分化、增殖、分裂和运动,(4)蛋白质通过膜的易位,(5)细胞内囊泡的运输,以及囊泡介导的分泌和摄取,通过GTP酶控制囊泡外壳组装。Oncogene侧是诱发癌症的基因。
我公司将向你提供以下的独一无二的三种抗体或者试剂盒: (1) 仅识别 GTP酶的活性构型的产品, 它可以让你能够量化GTP酶在细胞中的活性和分布。(2) 识别突变 Oncogene蛋白, 但不认识相应野生型的抗体。 (3) 对 cAMP 和 cGMP 具有超亲和力(无需乙酰化)ELISA检测试剂盒。这些产品被将近一千篇同行评议的文章所引用。
¥5,800.00
目录: 28416 |
产品名称: Biotinylated PSCA(DM87) Rabbit Monoclonal Antibody |
基因符号: PSCA;UNQ206;PRO232 |
描述: Biotinylated PSCA antibody(DM87) Rabbit Monoclonal Antibody |
背景: This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder; placenta; colon; kidney; and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals; this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants. |
经过测试的应用: ELISA; Flow Cyt |
推荐稀释度: ELISA 1:5000-10000; Flow Cyt 1:100 |
种属反应性: Rabbit |
亚型: Rabbit IgG |
纯化: Purified from cell culture supernatant by affinity chromatography |
种属反应性: Human PSCA |
成分: Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization. |
储存和运输: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). |
![]() Figure 1. 1e5 of Expi 293 cell line transfected with human PSCA were stained with 100 µl of 1:100 diluted Biotinylated PSCA antibody (DM87), Rabbit mAb (Red histogram) or isotype control (Blue histogram) respectively, washed and then stained with Streptavidin APC. The experimental samples were analyzed by flow cytometry. |