武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处 

邮箱: 2716620741@qq.com

咨询: 027 – 63497286 

英文
英文

Biotinylated Anti-CD40 (DM100) Rabbit mAb

Biotinylated Anti-CD40 (DM100) Rabbit Monoclonal Antibody
5/5

¥5,800.00

Cat.#:  28443

   Size:   100 μg

2-3 weeks

          Product Description          
目录:   28443
产品名称:   Biotinylated CD40(DM100) Rabbit Monoclonal Antibody
基因符号:   CD40; Bp50; CDW40; MGC9013; TNFRSF5; p50
描述:    Biotinylated CD40 antibody(DM100) Rabbit Monoclonal Antibody
背景:    This gene is a member of the TNF-receptor superfamily. The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching; memory B cell development; and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand; which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation; and thus is thought to be an early event in Alzheimer disease pathogenesis. Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3). Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
经过测试的应用:    ELISA; Flow Cyt
推荐稀释度:    ELISA 1:5000-10000; Flow Cyt 1:100
种属反应性:    Rabbit
亚型:    Rabbit IgG
纯化:    Purified from cell culture supernatant by affinity chromatography
种属反应性:    Human CD40
成分:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
储存和运输:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).
          Publications