武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处 

邮箱: 2716620741@qq.com

咨询: 027 – 63497286 

英文
英文

B7-H3 (DM53) Rabbit mAb

Anti-B7-H3 (DM53) Rabbit Monoclonal Antibody
5/5

¥3,900.00

Cat.#:  28351

   Size:   100 μg

In Stock

          Product Description          
目录:   28351
产品名称:   B7-H3(DM53) Rabbit Monoclonal Antibody
基因符号:   B7-H3; CD276; B7 homolog 3; B7H3
描述:    B7-H3 antibody(DM53) Rabbit Monoclonal Antibody
背景:    The protein encoded by this gene belongs to the immunoglobulin superfamily; and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors; the protein is preferentially expressed only in tumor tissues. Additionally; it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA; and there is an inverse correlation between the expression of this protein and miR29 levels; suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
经过测试的应用:    ELISA; Flow Cyt
推荐稀释度:    ELISA 1:5000-10000; Flow Cyt 1:100
种属反应性:    Rabbit
亚型:    Rabbit IgG
纯化:    Purified from cell culture supernatant by affinity chromatography
种属反应性:    Human B7-H3
成分:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
储存和运输:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry data of serially titrated Rabbit B7H3 monoclonal antibody ( clone: DM53) on on Expi 293 cell line transfected with human B7-H3. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.

Figure 2. Expi 293 cell line transfected with irrelevant protein  (A) and human B7-H3  (B) were surface stained with Rabbit B7-H3 monoclonal antibody 1µg/ml ( clone: DM53) followed by Alexa 488-conjugated rabbit IgG secondary antibody.
          Publications