Cat.#: S216276 |
Product Name: Anti-COX16 Rabbit Polyclonal Antibody |
Synonyms: hCOX16; HSPC203; C14orf112 |
UNIPROT ID: Q9P0S2 (Gene Accession – BC001702 ) |
Background: Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase (PubMed:29355485, PubMed:29381136). Promotes the insertion of copper into the active site of cytochrome c oxidase subunit II (MT-CO2/COX2) (PubMed:29355485, PubMed:29381136). Interacts specifically with newly synthesized MT-CO2/COX and its copper center-forming metallochaperones SCO1, SCO2 and COA6 (PubMed:29381136). Probably facilitates MT-CO2/COX2 association with the MITRAC assembly intermediate containing MT-CO1/COX1, thereby participating in merging the MT-CO1/COX1 and MT-CO2/COX2 assembly lines (PubMed:29381136). |
Immunogen: Fusion protein of human COX16 |
Applications: ELISA, IHC |
Recommended Dilutions: IHC: 25-100; ELISA: 500-2000 |
Host Species: Rabbit |
Clonality: Rabbit Polyclonal |
Isotype: Immunogen-specific rabbit IgG |
Purification: Antigen affinity purification |
Species Reactivity: Human, Mouse |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
Research Areas: Metabolism |
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin-embedded Human liver cancer tissue using 216276(COX16 Antibody) at a dilution of 1/50(Cytoplasm, Cell membrane). | Immunohistochemistry analysis of paraffin-embedded Human tonsil tissue using 216276(Anti-COX16 Antibody) at a dilution of 1/50. |
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