武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处 

邮箱: 2716620741@qq.com

咨询: 027 – 63497286 

英文
英文

APP(3D7) IgG1 Chimeric mAb

Anti-APP antibody(3D7) IgG1 Chimeric Monoclonal Antibody
5/5

¥3,900.00

Cat.#:  28565

   Size:   100 µg

In Stock

          Product Description          
目录:   28565
产品名称:   APP(3D7) IgG1 Chimeric Monoclonal Antibody
基因符号:   AAA;ABETA;ABPP;AD1;APPI;CTFgamma;CVAP;PN-II;PN2;preA4
描述:    APP antibody(3D7) IgG1 Chimeric Monoclonal Antibody
背景:    This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014]
经过测试的应用:    Flow Cyt
推荐稀释度:    Flow Cyt 1/100
种属反应性:    Rabbit
亚型:    Rabbit/Human Fc chimeric IgG1
纯化:    Purified from cell culture supernatant by affinity chromatography
种属反应性:    Human APP
成分:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).
Figure 1. Flow cytometry analysis with APP (3D7) mAb on Expi293 cells transfected with human APP (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
          Publications