Cat.#: S220296 |
Product Name: Anti-APBA2 Rabbit Polyclonal Antibody |
Synonyms: X11L; MINT2; LIN-10; HsT16821; X11-BETA; D15S1518E; MGC:14091 |
UNIPROT ID: Q99767 (Gene Accession – NP_001123886 ) |
Background: The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer’s disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer’s disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene. |
Immunogen: Synthetic peptide of human APBA2 |
Applications: ELISA, IHC |
Recommended Dilutions: IHC: 100-300; ELISA: 2000-5000 |
Host Species: Rabbit |
Clonality: Rabbit Polyclonal |
Isotype: Immunogen-specific rabbit IgG |
Purification: Antigen affinity purification |
Species Reactivity: Human |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
Research Areas: Neuroscience |
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 220296(APBA2 Antibody) at a dilution of 1/80(Cytoplasm). | In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 220296(Anti-APBA2 Antibody) at dilution 1/80. | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 220296(Anti-APBA2 Antibody) at a dilution of 1/80. | In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with synthetic peptide and then with D261289(Anti-APBA2 Antibody) at dilution 1/80. |
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