| 目录: 28342 |
| 产品名称: ACE2(DM48) Rabbit Monoclonal Antibody |
| 基因符号: ACE-2; ACEH; ACE2 |
| 描述: ACE2 antibody(DM48) Rabbit Monoclonal Antibody |
| 背景: The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9; and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function; as well as fertility. In addition; the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63. |
| 经过测试的应用: ELISA; Flow Cyt |
| 推荐稀释度： ELISA 1:5000-10000; Flow Cyt 1:100 |
| 种属反应性: Rabbit |
| 亚型: Rabbit IgG |
| 纯化: Purified from cell culture supernatant by affinity chromatography |
| 种属反应性: Human ACE2 |
| 成分: Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization. |
| 储存和运输: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). |
 
Figure 1. Expi 293 cell line transfected with irrelevant protein (left) and human ACE2 (right) were surface stained with Rabbit ACE2 monoclonal antibody 1µg/ml ( clone: DM48) followed by Alexa 488-conjugated rabbit IgG secondary antibody. | 
Figure 2. Flow cytometry data of serially titrated Rabbit ACE2 monoclonal antibody ( clone: DM48) on Expi 293 cell line transfected with human ACE2. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used. | 
Figure 3. Affinity ranking of different Rabbit ACE2 mAb clones by titration of different concentration onto Expi 293 cell line transfected with human ACE2. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used. | |
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