武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处 

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Anti-MMAE Monoclonal antibody (8B4)

Anti-MMAE Monoclonal antibody (8B4)
5/5

¥4,050.00

Cat.#:  26105

   Size:   100 µL

In Stock

          Product Description          
MMAE Monoclonal antibody (8B4)
货号:   26105
规格:  100 µL
描述:   MMAE Monoclonal antibody(8B4)
背景: Monomethyl auristatin E (MMAE), a potent mitotic inhibitor derived from dolastatin 10, plays a pivotal role in antibody-drug conjugates (ADCs) for cancer therapy. ADCs precisely target cancer cells, minimizing collateral damage. However, ADC development requires thorough pharmacokinetic and safety assessments. Our specialized MMAE antibodies streamline this process, facilitating PK analysis and safety evaluation. These antibodies are crucial tools for optimizing ADCs, ensuring their effectiveness and safety in revolutionizing cancer treatment.
免疫原:   Monomethyl auristatin E
经过测试的应用:   ELISA
推荐稀释度:   ELISA 1:5000-10000
浓度:    1 mg/ml
种属反应性:   Rabbit
克隆性:   Monoclonal
Clone ID:    8B4
亚型:    Rabbit IgG
纯化::   Purified from cell culture supernatant by affinity chromatography
Formulation & Reconstitution:Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
储存条件::   Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
image.png Figure 1. Elisa plates were pre-coated with IgG-MMAE (0.2 μg/per well). Serial diluted MMAE monoclonal antibody (26105) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for MMAE monoclonal antibody binding with IgG-MMAE is 2.274 ng/ml.
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