Cat.#: S219691 |
Product Name: Anti-CEACAM5 Rabbit Polyclonal Antibody |
Synonyms: CEA; CD66e |
UNIPROT ID: P06731 (Gene Accession – BC034671 ) |
Background: This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. |
Immunogen: Synthetic peptide of human CEACAM5 |
Applications: ELISA, IHC |
Recommended Dilutions: IHC: 50-200; ELISA: 5000-10000 |
Host Species: Rabbit |
Clonality: Rabbit Polyclonal |
Isotype: Immunogen-specific rabbit IgG |
Purification: Antigen affinity purification |
Species Reactivity: Human |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
Research Areas: Immunology, Cell Markers, Stem Cells, Cancer |
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human colorectal cancer tissue using 219691(CEACAM5 Antibody) at a dilution of 1/50(Cytoplasm and Cell membrane). | In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with the synthetic peptide and then with 219691(Anti-CEACAM5 Antibody) at dilution 1/50. | The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 219691(Anti-CEACAM5 Antibody) at a dilution of 1/50. | In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with synthetic peptide and then with D260161(Anti-CEACAM5 Antibody) at dilution 1/50. |
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